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Classification Of Enzymes In Biochemistry Pdf Download

Classification Of Enzymes In Biochemistry Pdf Download

classification of enzymes in biochemistry pdf

 

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Classification Of Enzymes In Biochemistry Pdf Download

 

Enzyme,,nomenclature,,1992:,,recommendations,,of,,the,,Nomenclature,,Committee,,of,,the,,International,,Union,,of,,Biochemistry,,and,,Molecular,,Biology,,on,,the,,nomenclature,,and,,classification,,of,,enzymes.,,Sometime,the,interconverstion,is,carried,out,by,an,intramolecular,oxidoreduction.,Enzymes,,are,,normally,,used,,for,,catalyzing,,the,,transfer,,of,,functional,,groups,,,electrons,,,or,,atoms.,,Hydrolases,,catalyze,,reactions,,that,,involve,,hydrolysis.,,EC,,4.1,,includes,,lyases,,that,,cleave,,carbon-carbon,,bonds,,,such,,as,,decarboxylases,,(EC,,4.1.1),,,aldehyde,,lyases,,(EC,,4.1.2),,,oxo,,acid,,lyases(EC,,4.1.3),,and,,others,,(EC,,4.1.99),,EC,,4.2,,includes,,lyases,,that,,cleave,,carbon-oxygen,,bonds,,,such,,as,,dehydratases,,EC,,4.3,,includes,,lyases,,that,,cleave,,carbon-nitrogen,,bonds,,EC,,4.4,,includes,,lyases,,that,,cleave,,carbon-sulfur,,bonds,,EC,,4.5,,includes,,lyases,,that,,cleave,,carbon-halide,,bonds,,EC,,4.6,,includes,,lyases,,that,,cleave,,phosphorus-oxygen,,bonds,,,such,,as,,adenylate,,cyclase,,and,,guanylate,,cyclase,,EC,,4.99,,includes,,other,,lyases,,,such,,as,,ferrochelatase,,.,,This,,allowed,,for,,the,,addition,,of,,a,,four-digit,,number,,that,,would,,precede,,EC(Enzyme,,Commission),,and,,each,,enzyme,,could,,be,,identified.,,San,Diego:,Published,for,the,International,Union,of,Biochemistry,and,Molecular,Biology,by,Academic,Press.,BIOCHEMISTRY.,,

 

When,,,a,,,substrate,,,is,,,being,,,oxidized,,,it,,,is,,,the,,,hydrogen,,,donor.,,,6th,,,ed.,,,For,,example:,,Chymotrypsin.,,The,,,transfer,,,occurs,,,from,,,one,,,molecule,,,that,,,will,,,be,,,the,,,donor,,,to,,,another,,,molecule,,,that,,,will,,,be,,,the,,,acceptor.,,,Hydrolases[edit].,,,

 

In,,,this,,,case,,,,one,,,molecule,,,is,,,both,,,the,,,hydrogen,,,acceptor,,,and,,,donor,,,,so,,,there's,,,no,,,oxidized,,,product.,,,,,Berg,,,Jeremy,,M.,,,John,,L.,,There,,were,,six,,classes,,of,,enzymes,,that,,were,,created,,so,,that,,enzymes,,could,,easily,,be,,named.,,Glutathione,S-transferase,.,The,reaction,that,an,enzyme,catalyzes,must,be,know,before,it,can,be,classified.[1].,Since,this,is,the,case,,they,are,assigned,names,by,the,type,of,reaction,they,catalyze.,

 

Transferases,,,catalyze,,,group,,,transfer,,,reactions.,,,The,,subclasses,,are,,created,,under,,this,,category,,by,,the,,type,,of,,isomerism.,,EC,,,2.1,,,includes,,,enzymes,,,that,,,transfer,,,one-carbon,,,groups,,,(methyltransferase),,,EC,,,2.2,,,includes,,,enzymes,,,that,,,transfer,,,aldehyde,,,or,,,ketone,,,groups,,,EC,,,2.3,,,includes,,,acyltransferases,,,EC,,,2.4,,,includes,,,glycosyltransferases,,,EC,,,2.5,,,includes,,,enzymes,,,that,,,transfer,,,alkyl,,,or,,,aryl,,,groups,,,,other,,,than,,,methyl,,,groups,,,EC,,,2.6,,,includes,,,enzymes,,,that,,,transfer,,,nitrogenous,,,groups,,,(transaminase),,,EC,,,2.7,,,includes,,,enzymes,,,that,,,transfer,,,phosphorus-containing,,,groups,,,(phosphotransferase,,,,including,,,polymerase,,,and,,,kinase),,,EC,,,2.8,,,includes,,,enzymes,,,that,,,transfer,,,sulfur-containing,,,groups,,,(sulfurtransferase,,,and,,,sulfotransferase),,,EC,,,2.9,,,includes,,,enzymes,,,that,,,transfer,,,selenium-containing,,,groups,,,.,,,These,,,enzymes,,,allow,,,for,,,structural,,,or,,,geometric,,,changes,,,within,,,a,,,compound.,,,Most,,,of,,,the,,,time,,,,the,,,donor,,,is,,,a,,,cofactor,,,that,,,is,,,charged,,,with,,,the,,,group,,,about,,,to,,,be,,,transferred.,,,An,oxidase,is,referred,to,when,the,oxygen,atom,is,the,acceptor.,ISBN0-12-227164-5.,EC,,,1.1,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,the,,,CH-OH,,,group,,,of,,,donors,,,(alcohol,,,oxidoreductases),,,EC,,,1.2,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,the,,,aldehyde,,,or,,,oxo,,,group,,,of,,,donors,,,EC,,,1.3,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,the,,,CH-CH,,,group,,,of,,,donors,,,(CH-CH,,,oxidoreductases),,,EC,,,1.4,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,the,,,CH-NH2,,,group,,,of,,,donors,,,(Amino,,,acid,,,oxidoreductases,,,,Monoamine,,,oxidase),,,EC,,,1.5,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,CH-NH,,,group,,,of,,,donors,,,EC,,,1.6,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,NADH,,,or,,,NADPH,,,EC,,,1.7,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,other,,,nitrogenous,,,compounds,,,as,,,donors,,,EC,,,1.8,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,a,,,sulfur,,,group,,,of,,,donors,,,EC,,,1.9,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,a,,,heme,,,group,,,of,,,donors,,,EC,,,1.10,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,diphenols,,,and,,,related,,,substances,,,as,,,donors,,,EC,,,1.11,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,peroxide,,,as,,,an,,,acceptor,,,(peroxidases),,,EC,,,1.12,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,hydrogen,,,as,,,donors,,,EC,,,1.13,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,single,,,donors,,,with,,,incorporation,,,of,,,molecular,,,oxygen,,,(oxygenases),,,EC,,,1.14,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,paired,,,donors,,,with,,,incorporation,,,of,,,molecular,,,oxygen,,,EC,,,1.15,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,superoxide,,,radicals,,,as,,,acceptors,,,EC,,,1.16,,,includes,,,oxidoreductases,,,that,,,oxidize,,,metal,,,ions,,,EC,,,1.17,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,CH,,,or,,,CH2,,,groups,,,EC,,,1.18,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,iron-sulfur,,,proteins,,,as,,,donors,,,EC,,,1.19,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,reduced,,,flavodoxin,,,as,,,a,,,donor,,,EC,,,1.20,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,phosphorus,,,or,,,arsenic,,,in,,,donors,,,EC,,,1.21,,,includes,,,oxidoreductases,,,that,,,act,,,on,,,X-H,,,and,,,Y-H,,,to,,,form,,,an,,,X-Y,,,bond,,,EC,,,1.97,,,includes,,,other,,,oxidoreductases,,,.,,,This,,cases,,usually,,involves,,the,,transfer,,of,,functional,,groups,,to,,water.,,

 

For,,,example:,,,phosphoglucose,,,isomerase,,,for,,,converting,,,glucose,,,6-phosphate,,,to,,,fructose,,,6-phosphate.,,,H.,,,These,,,enzymes,,,could,,,also,,,be,,,classified,,,under,,,transferaes,,,since,,,hydrolysis,,,can,,,be,,,viewed,,,as,,,a,,,transfer,,,of,,,a,,,functional,,,group,,,to,,,water,,,as,,,an,,,acceptor.,,,Isomerases,catalyze,reactions,that,transfer,functional,groups,within,a,molecule,so,that,isomeric,forms,are,produced.,Ligases,,are,,used,,in,,catalysis,,where,,two,,substrates,,are,,litigated,,and,,the,,formation,,of,,carbon-carbon,,,carbon-sulfide,,,carbon-nitrogen,,,and,,carbon-oxygen,,bonds,,due,,to,,condensation,,reactions.,,Oxidoreductases[edit].,,, 65288a64fe

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